The 2-1-1 Method: On-Demand PrEP, Explained
How 2-1-1 (on-demand) PrEP works – the exact dosing schedule, who it is for and who it is not, how well it works, and how it compares to daily PrEP.
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Sexual Health
PrEP Side Effects: What’s Real, What’s Rare, and How We Monitor
Short-term and long-term side effects of PrEP – Truvada, Descovy, and injectable Apretude – plus drug interactions, PrEP with hormone therapy, and how monitoring keeps you safe.
October 14, 2026
Gender-Affirming Care
Fertility and GAHT: What to Know Before, During, and After Hormone Therapy
How gender-affirming hormone therapy affects fertility, what is reversible and what is not, and your preservation options – based on WPATH SOC-8 and UCSF guidelines.
October 14, 2026
Gender-Affirming Care
Antiandrogens in GAHT: What Blockers Do, Their Side Effects, and What to Expect
A guide to testosterone blockers in feminizing hormone therapy – spironolactone, finasteride, GnRH agonists – their side effects, monitoring, and what to expect, based on WPATH and UCSF guidelines.
October 14, 2026
Sexual Health
DoxyPEP, Explained: One Pill After Sex That Helps Prevent STIs
DoxyPEP is a single dose of doxycycline taken after sex that sharply cuts the risk of syphilis, chlamydia, and gonorrhea. Who it is for, how it works, and how to get it.
October 5, 2026
Gender-Affirming Care
Self-Injecting Estradiol or Testosterone in 11 Easy Steps
A step-by-step guide to self-injecting estradiol valerate or testosterone for gender-affirming hormone therapy – supplies, technique, sites, and troubleshooting.
October 5, 2026
Sexual Health
Herpes Blood Tests: Why We Don’t Order Them
Herpes is deliberately left off standard STI screening – and both the USPSTF and CDC say so explicitly. Here is the reasoning, and what we do instead.
September 9, 2026